Study: Eating more than 45% of calorie intake after 5 p.m. alters glucose levels, with serious consequences for health

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The time of day when we eat is crucial for our health

Credit: Nutrition & Diabetes (2024). DOI: 10.1038/s41387-024-00347-6

Although people have always said that having a light and early dinner is better, a study by the Universitat Oberta de Catalunya (UOC) and Columbia University has provided the scientific grounds for this argument.

According to a study published in Nutrition & Diabetes, consuming more than 45% of our daily calorie intake after 5 p.m. is associated with an increase in glucose levels, with the harmful consequences that this has for health, regardless of the individual's weight and body fat.

The study was carried out at Columbia University's Irving Medical Center in New York, and was led by Dr. Diana Díaz Rizzolo, postdoctoral researcher and member of the Faculty of Health Sciences at the UOC.

"Maintaining high levels of glucose over long periods of time can have implications including a higher risk of progressing to type 2 diabetes, an increase in cardiovascular risk due to the damage that high glucose levels do to blood vessels, and increased chronic inflammation, which aggravates cardiovascular and metabolic damage," said Díaz Rizzolo.

Experts had previously believed that the main consequence of eating dinner late in the day was weight gain. This was associated with the fact that people tend to make poorer dietary choices at night, such as consuming more ultra-processed foods, since the hormones that regulate hunger and satiety are altered when people do not eat during daylight hours.

The importance of the study lies in the fact that it shows that the time of day when meals are eaten can in itself have a negative impact on glucose metabolism, regardless of the amount of calories consumed throughout the day and the individual's weight and body fat.

Late eaters versus early eaters

The study included 26 participants between the ages of 50 and 70 who were overweight or obese, and had prediabetes or type 2 diabetes. The participants' glucose tolerance levels were compared, and they were divided into two groups: early eaters, who consumed most of their daily calories before the evening, and late eaters, who consumed 45% or more of their calories after 5 p.m.

The two groups consumed the same amount of calories and the same foods during the day, but did so at different times. The participants used a mobile app to record their meals in real time.

The main finding of the study is that the late eaters had a poorer tolerance of glucose, regardless of their weight or the composition of their diet. It also found that they tended to eat larger amounts of carbohydrates and fats during the evening.

Díaz Rizzolo, who is an expert on issues related to obesity, diabetes and aging, explained that "the body's ability to metabolize glucose is limited at night, because the secretion of insulin is reduced, and our cells' sensitivity to this hormone declines due to the circadian rhythm, which is determined by a central clock in our brain that is coordinated with the hours of daylight and night."

The importance of eating at the right time

The study therefore contains an important finding in terms of its implications for health and the time of day that people eat their meals. "Until now, personal decisions in nutrition have been based on two main questions: how much we eat, and what foods to choose. With this study, a new factor in cardiometabolic health is beginning to become increasingly important: when we eat," said Díaz Rizzolo.

In view of the results of the study, and considering them with due caution, since further research to gain a greater understanding of the subject will be required, the researcher advises that food should mainly be eaten during daylight hours, and that "the highest levels of calorie intake during the day should be at breakfast and lunch, instead of at teatime and dinner." Díaz Rizzolo also recommends avoiding eating ultra-processed products, fast food and foods rich in carbohydrates, especially at night.

More information: Diana A. Díaz-Rizzolo et al, Late eating is associated with poor glucose tolerance, independent of body weight, fat mass, energy intake and diet composition in prediabetes or early onset type 2 diabetes, Nutrition & Diabetes (2024). DOI: 10.1038/s41387-024-00347-6

Citation: Study: Eating more than 45% of calorie intake after 5 p.m. alters glucose levels, with serious consequences for health (2024, November 19) retrieved 20 November 2024 from https://medicalxpress.com/news/2024-11-calorie-intake-pm-glucose-consequences.html

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一项由加泰罗尼亚开放大学和哥伦比亚大学进行的研究表明,晚餐时间对健康至关重要。研究发现,晚于下午5点摄入超过45%的日常热量与血糖水平升高相关,可能导致2型糖尿病、心血管风险增加及慢性炎症等健康问题。研究对象为26名50至70岁之间的超重或肥胖者,结果显示,晚餐吃得较晚的人血糖耐受性较差,尽管他们的热量摄入和饮食成分相同。研究指出,夜间身体代谢葡萄糖的能力有限,胰岛素分泌减少,细胞对胰岛素的敏感性下降。因此,研究建议人们应在白天摄入更多热量,尤其是在早餐和午餐时,避免夜间摄入过多的超加工食品和高碳水化合物食物。