Osteomalazie – Klinik, Diagnostik und Therapie

contenido
  1. Cashman KD, Dowling KG, Škrabáková Z, Gonzalez-Gross M, Valtueña J, De Henauw S et al (2016) Vitamin D deficiency in Europe: pandemic? Am J Clin Nutr 103(4):1033. https://doi.org/10.3945/ajcn.115.120873
[Article](https://doi.org/10.3945%2Fajcn.115.120873)  [CAS](https://link.springer.com/articles/cas-redirect/1:CAS:528:DC%2BC28Xht1amtLbK)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=26864360)  [PubMed Central](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527850)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Vitamin%20D%20deficiency%20in%20Europe%3A%20pandemic%3F&journal=Am%20J%20Clin%20Nutr&doi=10.3945%2Fajcn.115.120873&volume=103&issue=4&publication_year=2016&author=Cashman%2CKD&author=Dowling%2CKG&author=%C5%A0krab%C3%A1kov%C3%A1%2CZ&author=Gonzalez-Gross%2CM&author=Valtue%C3%B1a%2CJ&author=Henauw%2CS) 
  1. Girgis CM, Clifton-Bligh RJ, Hamrick MW, Holick MF, Gunton JE (2013) The roles of vitamin D in skeletal muscle: form, function, and metabolism. Endocr Rev 34(1):33. https://doi.org/10.1210/er.2012-1012
[Article](https://doi.org/10.1210%2Fer.2012-1012)  [CAS](https://link.springer.com/articles/cas-redirect/1:CAS:528:DC%2BC3sXjs1Ors78%3D)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23169676)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=The%20roles%20of%20vitamin%20D%20in%20skeletal%20muscle%3A%20form%2C%20function%2C%20and%20metabolism&journal=Endocr%20Rev&doi=10.1210%2Fer.2012-1012&volume=34&issue=1&publication_year=2013&author=Girgis%2CCM&author=Clifton-Bligh%2CRJ&author=Hamrick%2CMW&author=Holick%2CMF&author=Gunton%2CJE) 
  1. Reuss-Borst M, Lange U (2017) Metabolische Knochenkrankheit: Osteomalazie. Aktuelle Rheumatol 42:228. https://doi.org/10.1055/s-0042-118697
[Article](https://doi.org/10.1055%2Fs-0042-118697)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Metabolische%20Knochenkrankheit%3A%20Osteomalazie&journal=Aktuelle%20Rheumatol&doi=10.1055%2Fs-0042-118697&volume=42&publication_year=2017&author=Reuss-Borst%2CM&author=Lange%2CU) 
  1. Blann A (2015) An update on vitamin D deficiency and at risk groups. J Fam Health 25:16–19
[PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=26118289)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=An%20update%20on%20vitamin%20D%20deficiency%20and%20at%20risk%20groups&journal=J%20Fam%20Health&volume=25&pages=16-19&publication_year=2015&author=Blann%2CA) 
  1. Cozzolino M, Vidal M, Arcidiacono MV, Tebas P, Yarasheski KE, Dusso AS (2003) HIV-protease inhibitors impair vitamin D bioactivation to 1,25-dihydroxyvitamin D. AIDS. https://doi.org/10.1097/01.aids.0000050817.06065.f8
[Article](https://doi.org/10.1097%2F01.aids.0000050817.06065.f8)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12598771)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=HIV-protease%20inhibitors%20impair%20vitamin%20D%20bioactivation%20to%201%2C25-dihydroxyvitamin%20D&journal=AIDS&doi=10.1097%2F01.aids.0000050817.06065.f8&publication_year=2003&author=Cozzolino%2CM&author=Vidal%2CM&author=Arcidiacono%2CMV&author=Tebas%2CP&author=Yarasheski%2CKE&author=Dusso%2CAS) 
  1. Welz T, Childs K, Ibrahim F, Poulton M, Taylor CB, Moniz CF et al (2010) Efavirenz is associated with severe vitamin D deficiency and increased alkaline phosphatase. AIDS. https://doi.org/10.1097/QAD.0b013e32833c3281
[Article](https://doi.org/10.1097%2FQAD.0b013e32833c3281)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20588161)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Efavirenz%20is%20associated%20with%20severe%20vitamin%20D%20deficiency%20and%20increased%20alkaline%20phosphatase&journal=AIDS&doi=10.1097%2FQAD.0b013e32833c3281&publication_year=2010&author=Welz%2CT&author=Childs%2CK&author=Ibrahim%2CF&author=Poulton%2CM&author=Taylor%2CCB&author=Moniz%2CCF) 
  1. Skversky AL, Kumar J, Abramowitz MK, Kaskel FJ, Melamed ML (2011) Association of glucocorticoid use and low 25-hydroxyvitamin D levels: results from the National Health and Nutrition Examination Survey (NHANES): 2001–2006. J Clin Endocrinol Metab. https://doi.org/10.1210/jc.2011-1600
[Article](https://doi.org/10.1210%2Fjc.2011-1600)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21956424)  [PubMed Central](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232615)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Association%20of%20glucocorticoid%20use%20and%20low%2025-hydroxyvitamin%20D%20levels%3A%20results%20from%20the%20National%20Health%20and%20Nutrition%20Examination%20Survey%20%28NHANES%29%3A%202001%E2%80%932006&journal=J%20Clin%20Endocrinol%20Metab&doi=10.1210%2Fjc.2011-1600&publication_year=2011&author=Skversky%2CAL&author=Kumar%2CJ&author=Abramowitz%2CMK&author=Kaskel%2CFJ&author=Melamed%2CML) 
  1. Gröber U, Kisters K (2012) Influence of drugs on vitamin D and calcium metabolism. Dermatoendocrinol. https://doi.org/10.4161/derm.20731
[Article](https://doi.org/10.4161%2Fderm.20731)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22928072)  [PubMed Central](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427195)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Influence%20of%20drugs%20on%20vitamin%20D%20and%20calcium%20metabolism&journal=Dermatoendocrinol&doi=10.4161%2Fderm.20731&publication_year=2012&author=Gr%C3%B6ber%2CU&author=Kisters%2CK) 
  1. Liamis G, Milionis HJ, Elisaf M (2010) Medication-induced hypophosphatemia: a review. QJM. https://doi.org/10.1093/qjmed/hcq039
[Article](https://doi.org/10.1093%2Fqjmed%2Fhcq039)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20356849)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Medication-induced%20hypophosphatemia%3A%20a%20review&journal=QJM&doi=10.1093%2Fqjmed%2Fhcq039&publication_year=2010&author=Liamis%2CG&author=Milionis%2CHJ&author=Elisaf%2CM) 
  1. Reese DM, Rosen PJ (1997) Oncogenic osteomalacia associated with prostate cancer. J Urol. https://doi.org/10.1016/S0022-5347(01)64351-9
[Article](https://doi.org/10.1016%2FS0022-5347%2801%2964351-9)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9258108)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Oncogenic%20osteomalacia%20associated%20with%20prostate%20cancer&journal=J%20Urol&doi=10.1016%2FS0022-5347%2801%2964351-9&publication_year=1997&author=Reese%2CDM&author=Rosen%2CPJ) 
  1. Konishi K, Nakamura M, Yamakawa H, Suzuki H, Saruta T, Hanaoka H et al (1991) Hypophosphatemic osteomalacia in von Recklinghausen neurofibromatosis. Am J Med Sci 301(5):322–328
[Article](https://doi.org/10.1097%2F00000441-199105000-00006)  [CAS](https://link.springer.com/articles/cas-redirect/1:STN:280:DyaK3M3htl2htg%3D%3D)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Hypophosphatemic%20osteomalacia%20in%20von%20Recklinghausen%20neurofibromatosis&journal=Am%20J%20Med%20Sci&doi=10.1097%2F00000441-199105000-00006&volume=301&issue=5&pages=322-328&publication_year=1991&author=Konishi%2CK&author=Nakamura%2CM&author=Yamakawa%2CH&author=Suzuki%2CH&author=Saruta%2CT&author=Hanaoka%2CH) 
  1. Taylor HC, Fallon MD, Velasco ME (1984) Oncogenic osteomalacia and inappropriate antidiuretic hormone secretion due to oat-cell carcinoma. Ann Intern Med 101(6):786–768
[Article](https://doi.org/10.7326%2F0003-4819-101-6-786)  [CAS](https://link.springer.com/articles/cas-redirect/1:STN:280:DyaL2M%2FksFWgug%3D%3D)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Oncogenic%20osteomalacia%20and%20inappropriate%20antidiuretic%20hormone%20secretion%20due%20to%20oat-cell%20carcinoma&journal=Ann%20Intern%20Med&doi=10.7326%2F0003-4819-101-6-786&volume=101&issue=6&pages=786-768&publication_year=1984&author=Taylor%2CHC&author=Fallon%2CMD&author=Velasco%2CME) 
  1. Reuss-Borst MA (2014) Metabolic bone disease osteomalacia. Z Rheumatol. https://doi.org/10.1007/s00393-013-1285-8
[Article](https://link.springer.com/doi/10.1007/s00393-013-1285-8)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24811356)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Metabolic%20bone%20disease%20osteomalacia&journal=Z%20Rheumatol&doi=10.1007%2Fs00393-013-1285-8&publication_year=2014&author=Reuss-Borst%2CMA) 
  1. Bohannon RW (2001) Dynamometer measurements of hand-grip strength predict multiple outcomes. Percept Mot Skills. https://doi.org/10.2466/pms.2001.93.2.323
[Article](https://doi.org/10.2466%2Fpms.2001.93.2.323)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11769883)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Dynamometer%20measurements%20of%20hand-grip%20strength%20predict%20multiple%20outcomes&journal=Percept%20Mot%20Skills&doi=10.2466%2Fpms.2001.93.2.323&publication_year=2001&author=Bohannon%2CRW) 
  1. Cranney A, Horsley T, O’Donnell S, Weiler H, Puil L, Ooi D et al (2007) Effectiveness and safety of vitamin D in relation to bone health. Evid Rep Technol Assess (Full Rep) 2007(158):1–235
[Google Scholar](http://scholar.google.com/scholar_lookup?&title=Effectiveness%20and%20safety%20of%20vitamin%20D%20in%20relation%20to%20bone%20health&journal=Evid%20Rep%20Technol%20Assess%20%28Full%20Rep%29&volume=2007&issue=158&pages=1-235&publication_year=2007&author=Cranney%2CA&author=Horsley%2CT&author=O%E2%80%99Donnell%2CS&author=Weiler%2CH&author=Puil%2CL&author=Ooi%2CD) 
  1. Bours PHA, Wielders JPM, Vermeijden JR, van de Wiel A (2011) Seasonal variation of serum 25-hydroxyvitamin D levels in adult patients with inflammatory bowel disease. Osteoporos Int. https://doi.org/10.1007/s00198-010-1484-y
[Article](https://link.springer.com/doi/10.1007/s00198-010-1484-y)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21113577)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Seasonal%20variation%20of%20serum%2025-hydroxyvitamin%20D%20levels%20in%20adult%20patients%20with%20inflammatory%20bowel%20disease&journal=Osteoporos%20Int&doi=10.1007%2Fs00198-010-1484-y&publication_year=2011&author=Bours%2CPHA&author=Wielders%2CJPM&author=Vermeijden%2CJR&author=Wiel%2CA) 
  1. Dumitrescu G, Mihai C, Dranga M, Prelipcean CC (2014) Serum 25-hydroxyvitamin D concentration and inflammatory bowel disease characteristics in Romania. World J Gastroenterol. https://doi.org/10.3748/wjg.v20.i9.2392
[Article](https://doi.org/10.3748%2Fwjg.v20.i9.2392)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=25469022)  [PubMed Central](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248197)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Serum%2025-hydroxyvitamin%20D%20concentration%20and%20inflammatory%20bowel%20disease%20characteristics%20in%20Romania&journal=World%20J%20Gastroenterol&doi=10.3748%2Fwjg.v20.i9.2392&publication_year=2014&author=Dumitrescu%2CG&author=Mihai%2CC&author=Dranga%2CM&author=Prelipcean%2CCC) 
  1. Larsen S, Bendtzen K, Nielsen O (2010) Extraintestinal manifestations of infl ammatory bowel disease: epidemiology, diagnosis, and management. Ann Med 42(2):97–114
[Article](https://doi.org/10.3109%2F07853890903559724)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Extraintestinal%20manifestations%20of%20infl%20ammatory%20bowel%20disease%3A%20epidemiology%2C%20diagnosis%2C%20and%20management&journal=Ann%20Med&doi=10.3109%2F07853890903559724&volume=42&issue=2&pages=97-114&publication_year=2010&author=Larsen%2CS&author=Bendtzen%2CK&author=Nielsen%2CO) 
  1. Leitlinie des Dachverbands der Deutschsprachigen Wissenschaftlichen Osteologischen Gesellschaften e. V. zur Prophylaxe, Diagnostik und Therapie der OSTEOPOROSE bei postmenopausalen Frauen und bei Männern. 2017;
  1. Vestergaard P, Rejnmark L, Mosekilde L (2004) Fracture risk associated with use of antiepileptic drugs. Epilepsia. https://doi.org/10.1111/j.0013-9580.2004.18804.x
[Article](https://doi.org/10.1111%2Fj.0013-9580.2004.18804.x)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15509233)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Fracture%20risk%20associated%20with%20use%20of%20antiepileptic%20drugs&journal=Epilepsia&doi=10.1111%2Fj.0013-9580.2004.18804.x&publication_year=2004&author=Vestergaard%2CP&author=Rejnmark%2CL&author=Mosekilde%2CL) 
  1. Brown TT, Qaqish RB (2006) Antiretroviral therapy and the prevalence of osteopenia and osteoporosis: a meta-analytic review. AIDS. https://doi.org/10.1097/QAD.0b013e32801022eb
[Article](https://doi.org/10.1097%2FQAD.0b013e32801022eb)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17086056)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Antiretroviral%20therapy%20and%20the%20prevalence%20of%20osteopenia%20and%20osteoporosis%3A%20a%C2%A0meta-analytic%20review&journal=AIDS&doi=10.1097%2FQAD.0b013e32801022eb&publication_year=2006&author=Brown%2CTT&author=Qaqish%2CRB) 
  1. Takeda E, Yamamoto H, Taketani Y, Miyamoto K (1997) Vitamin D‑dependent rickets type I and type II. Acta Paediatr Jpn 39(4):508–513
[Article](https://doi.org/10.1111%2Fj.1442-200X.1997.tb03629.x)  [CAS](https://link.springer.com/articles/cas-redirect/1:CAS:528:DyaK2sXmsF2hurg%3D)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Vitamin%20D%E2%80%91dependent%20rickets%20type%20I%20and%20type%20II&journal=Acta%20Paediatr%20Jpn&doi=10.1111%2Fj.1442-200X.1997.tb03629.x&volume=39&issue=4&pages=508-513&publication_year=1997&author=Takeda%2CE&author=Yamamoto%2CH&author=Taketani%2CY&author=Miyamoto%2CK) 
  1. Kim CJ (2011) Vitamin D dependent rickets type I. Korean J Pediatr. https://doi.org/10.3345/kjp.2011.54.2.51
[Article](https://doi.org/10.3345%2Fkjp.2011.54.2.51)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22323909)  [PubMed Central](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274659)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Vitamin%20D%20dependent%20rickets%20type%20I&journal=Korean%20J%20Pediatr&doi=10.3345%2Fkjp.2011.54.2.51&publication_year=2011&author=Kim%2CCJ) 
  1. Malloy PJ, Feldman D (2010) Genetic disorders and defects in vitamin d action. Endocrinol Metab Clin North Am. https://doi.org/10.1016/j.ecl.2010.02.004
[Article](https://doi.org/10.1016%2Fj.ecl.2010.02.004)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20511055)  [PubMed Central](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879401)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Genetic%20disorders%20and%20defects%20in%20vitamin%20d%20action&journal=Endocrinol%20Metab%20Clin%20North%20Am&doi=10.1016%2Fj.ecl.2010.02.004&publication_year=2010&author=Malloy%2CPJ&author=Feldman%2CD) 
  1. Choudhury S, Jebasingh KF, Ranabir S, Singh T (2013) Familial vitamin D resistant rickets: End-organ resistance to 1,25-dihydroxyvitamin D. Indian J Endocrinol Metab 17(Suppl 1):S224–S227
[PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24251166)  [PubMed Central](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830312)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Familial%20vitamin%20D%20resistant%20rickets%3A%20End-organ%20resistance%20to%201%2C25-dihydroxyvitamin%20D&journal=Indian%20J%20Endocrinol%20Metab&volume=17&issue=Suppl%201&pages=S224-S227&publication_year=2013&author=Choudhury%2CS&author=Jebasingh%2CKF&author=Ranabir%2CS&author=Singh%2CT) 
  1. Halbritter J, Mayer C, Rasche FM, Amann K, Lindner TH (2009) Interstitielle Nephritis. Internist. https://doi.org/10.1007/s00108-009-2463-2
[Article](https://link.springer.com/doi/10.1007/s00108-009-2463-2)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19690821)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Interstitielle%20Nephritis&journal=Internist&doi=10.1007%2Fs00108-009-2463-2&publication_year=2009&author=Halbritter%2CJ&author=Mayer%2CC&author=Rasche%2CFM&author=Amann%2CK&author=Lindner%2CTH) 
  1. Elmonem MA, Veys KR, Soliman NA, Van Dyck M, Van Den Heuvel LP, Levtchenko E (2016) Cystinosis: a review. Orphanet J Rare Dis. https://doi.org/10.1186/s13023-016-0426-y
[Article](https://link.springer.com/doi/10.1186/s13023-016-0426-y)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=27102039)  [PubMed Central](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841061)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Cystinosis%3A%20a%20review&journal=Orphanet%20J%20Rare%20Dis&doi=10.1186%2Fs13023-016-0426-y&publication_year=2016&author=Elmonem%2CMA&author=Veys%2CKR&author=Soliman%2CNA&author=Dyck%2CM&author=Heuvel%2CLP&author=Levtchenko%2CE) 
  1. https://www.orpha.net/consor4.01/www/cgi-bin/OC_Exp.php?lng=DE&Expert=289176. Zugegriffen: 23.07.2018
  1. Hadji P, Klein S, Gothe H, Häussler B, Kless T, Schmidt T et al (2013) Epidemiologie der osteoporose: bone evaluation study. Dtsch Arztebl Int. https://doi.org/10.3238/arztebl.2013.0052
[Article](https://doi.org/10.3238%2Farztebl.2013.0052)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23826030)  [PubMed Central](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698909)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Epidemiologie%20der%20osteoporose%3A%20bone%20evaluation%20study&journal=Dtsch%20Arztebl%20Int&doi=10.3238%2Farztebl.2013.0052&publication_year=2013&author=Hadji%2CP&author=Klein%2CS&author=Gothe%2CH&author=H%C3%A4ussler%2CB&author=Kless%2CT&author=Schmidt%2CT) 
  1. Bingham CT, Fitzpatrick LA (1993) Noninvasive testing in the diagnosis of osteomalacia. Am J Med. https://doi.org/10.1016/0002-9343(93)90335-M
[Article](https://doi.org/10.1016%2F0002-9343%2893%2990335-M)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=7646591)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Noninvasive%20testing%20in%20the%20diagnosis%20of%20osteomalacia&journal=Am%20J%20Med&doi=10.1016%2F0002-9343%2893%2990335-M&publication_year=1993&author=Bingham%2CCT&author=Fitzpatrick%2CLA) 
  1. Chong WH, Yavuz S, Patel SM, Chen CC, Collins MT (2011) The importance of whole body imaging in tumor-induced osteomalacia. J Clin Endocrinol Metab. https://doi.org/10.1210/jc.2011-1757
[Article](https://doi.org/10.1210%2Fjc.2011-1757)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22143830)  [PubMed Central](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232632)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=The%20importance%20of%20whole%20body%20imaging%20in%20tumor-induced%20osteomalacia&journal=J%20Clin%20Endocrinol%20Metab&doi=10.1210%2Fjc.2011-1757&publication_year=2011&author=Chong%2CWH&author=Yavuz%2CS&author=Patel%2CSM&author=Chen%2CCC&author=Collins%2CMT) 
  1. Fukumoto S (2014) Diagnostic modalities for FGF23-producing tumors in patients with tumor-induced osteomalacia. Endocrinol Metab. https://doi.org/10.3803/EnM.2014.29.2.136
[Article](https://doi.org/10.3803%2FEnM.2014.29.2.136)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Diagnostic%20modalities%20for%20FGF23-producing%20tumors%20in%20patients%20with%20tumor-induced%20osteomalacia&journal=Endocrinol%20Metab&doi=10.3803%2FEnM.2014.29.2.136&publication_year=2014&author=Fukumoto%2CS) 
  1. Fukumoto S, Takeuchi Y, Nagano A, Fujita T (1999) Diagnostic utility of magnetic resonance imaging skeletal survey in a patient with oncogenic osteomalacia. Bone. https://doi.org/10.1016/S8756-3282(99)00170-2
[Article](https://doi.org/10.1016%2FS8756-3282%2899%2900170-2)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10495143)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Diagnostic%20utility%20of%20magnetic%20resonance%20imaging%20skeletal%20survey%20in%20a%C2%A0patient%20with%20oncogenic%20osteomalacia&journal=Bone&doi=10.1016%2FS8756-3282%2899%2900170-2&publication_year=1999&author=Fukumoto%2CS&author=Takeuchi%2CY&author=Nagano%2CA&author=Fujita%2CT) 
  1. Dupond JL, Mahammedi H, Prié D, Collin F, Gil H, Blagosklonov O et al (2005) Oncogenic osteomalacia: diagnostic importance of fibroblast growth factor 23 and F‑18 fluorodeoxyglucose PET/CT SCAN for the diagnosis and follow-up in one case. Bone. https://doi.org/10.1016/j.bone.2005.01.001
[Article](https://doi.org/10.1016%2Fj.bone.2005.01.001)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15777669)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Oncogenic%20osteomalacia%3A%20diagnostic%20importance%20of%20fibroblast%20growth%20factor%2023%20and%20F%E2%80%9118%20fluorodeoxyglucose%20PET%2FCT%20SCAN%20for%20the%20diagnosis%20and%20follow-up%20in%20one%20case&journal=Bone&doi=10.1016%2Fj.bone.2005.01.001&publication_year=2005&author=Dupond%2CJL&author=Mahammedi%2CH&author=Pri%C3%A9%2CD&author=Collin%2CF&author=Gil%2CH&author=Blagosklonov%2CO) 
  1. Ralston SH (2005) Structure and metabolism of bone. Medicine (Baltimore). https://doi.org/10.1383/medc.2005.33.12.58
[Article](https://doi.org/10.1383%2Fmedc.2005.33.12.58)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Structure%20and%20metabolism%20of%20bone&journal=Medicine%20%28Baltimore%29&doi=10.1383%2Fmedc.2005.33.12.58&publication_year=2005&author=Ralston%2CSH) 
  1. Kann PH, Pfützner A, Delling G, Schulz G, Meyer S (2006) Transiliac bone biopsy in osteoporosis: frequency, indications, consequences and complications. An evaluation of 99 consecutive cases over a period of 14 years. Clin Rheumatol. https://doi.org/10.1007/s10067-005-1132-7
[Article](https://link.springer.com/doi/10.1007/s10067-005-1132-7)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15915321)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Transiliac%20bone%20biopsy%20in%20osteoporosis%3A%20frequency%2C%20indications%2C%20consequences%20and%20complications.%20An%20evaluation%20of%2099%20consecutive%20cases%20over%20a%C2%A0period%20of%2014%20years&journal=Clin%20Rheumatol&doi=10.1007%2Fs10067-005-1132-7&publication_year=2006&author=Kann%2CPH&author=Pf%C3%BCtzner%2CA&author=Delling%2CG&author=Schulz%2CG&author=Meyer%2CS) 
  1. Rao DS, Matkovic VDH (1980) Transiliac bone biopsy: complications and diagnostic value. Henry Ford Hosp Med 28:112–118
[CAS](https://link.springer.com/articles/cas-redirect/1:STN:280:DyaL38%2FjtValtQ%3D%3D)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Transiliac%20bone%20biopsy%3A%20complications%20and%20diagnostic%20value&journal=Henry%20Ford%20Hosp.%20Med.&volume=28&pages=112-118&publication_year=1980&author=Rao%2CDS&author=Matkovic%2CVDH) 
  1. Siris ES, Clemens TL, Dempster DW, Shane E, Segre GV, Lindsay R et al (1987) Tumor-induced osteomalacia. Kinetics of calcium, phosphorus, and vitamin D metabolism and characteristics of bone histomorphometry. Am J Med. https://doi.org/10.1016/0002-9343(87)90075-1
[Article](https://doi.org/10.1016%2F0002-9343%2887%2990075-1)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=3812526)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Tumor-induced%20osteomalacia.%20Kinetics%20of%20calcium%2C%20phosphorus%2C%20and%20vitamin%20D%20metabolism%20and%20characteristics%20of%20bone%20histomorphometry&journal=Am%20J%20Med&doi=10.1016%2F0002-9343%2887%2990075-1&publication_year=1987&author=Siris%2CES&author=Clemens%2CTL&author=Dempster%2CDW&author=Shane%2CE&author=Segre%2CGV&author=Lindsay%2CR) 
  1. Parfitt AM, Pødenphant J, Villanueva AR, Frame B (1985) Metabolic bone disease with and without osteomalacia after intestinal bypass surgery: a bone histomorphometric study. Bone. https://doi.org/10.1016/8756-3282(85)90003-1
[Article](https://doi.org/10.1016%2F8756-3282%2885%2990003-1)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=3840379)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Metabolic%20bone%20disease%20with%20and%20without%20osteomalacia%20after%20intestinal%20bypass%20surgery%3A%20a%20bone%20histomorphometric%20study&journal=Bone&doi=10.1016%2F8756-3282%2885%2990003-1&publication_year=1985&author=Parfitt%2CAM&author=P%C3%B8denphant%2CJ&author=Villanueva%2CAR&author=Frame%2CB) 
  1. Priemel M, von Domarus C, Klatte TO, Kessler S, Schlie J, Meier S et al (2010) Bone mineralization defects and vitamin D deficiency: histomorphometric analysis of iliac crest bone biopsies and circulating 25-hydroxyvitamin D in 675 patients. J Bone Miner Res 2011(18):R53–R77
[Google Scholar](http://scholar.google.com/scholar_lookup?&title=Bone%20mineralization%20defects%20and%20vitamin%20D%20deficiency%3A%20histomorphometric%20analysis%20of%20iliac%20crest%20bone%20biopsies%20and%20circulating%2025-hydroxyvitamin%20D%20in%20675%E2%80%89patients&journal=J%20Bone%20Miner%20Res&volume=2011&issue=18&pages=R53-R57&publication_year=2010&author=Priemel%2CM&author=Domarus%2CC&author=Klatte%2CTO&author=Kessler%2CS&author=Schlie%2CJ&author=Meier%2CS) 
  1. Chong WH, Molinolo AA, Chen CC, Collins MT (2011) Tumor-induced osteomalacia. World J Surg Oncol 14:4. https://doi.org/10.1186/s12957-015-0763-7
[Article](https://link.springer.com/doi/10.1186/s12957-015-0763-7)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Tumor-induced%20osteomalacia&journal=Endocr%20Relat%20Cancer&doi=10.1186%2Fs12957-015-0763-7&volume=14&publication_year=2011&author=Chong%2CWH&author=Molinolo%2CAA&author=Chen%2CCC&author=Collins%2CMT) 
  1. Ovejero D, El-Maouche D, Brillante BA, Khosravi A, Gafni RI, Collins MT (2017) Octreotide is ineffective in treating tumor-induced osteomalacia: results of a short-term therapy. J Bone Miner Res. https://doi.org/10.1002/jbmr.3162
[Article](https://doi.org/10.1002%2Fjbmr.3162)  [PubMed](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=28459498)  [Google Scholar](http://scholar.google.com/scholar_lookup?&title=Octreotide%20is%20ineffective%20in%20treating%20tumor-induced%20osteomalacia%3A%20results%20of%20a%C2%A0short-term%20therapy&journal=J%20Bone%20Miner%20Res&doi=10.1002%2Fjbmr.3162&publication_year=2017&author=Ovejero%2CD&author=El-Maouche%2CD&author=Brillante%2CBA&author=Khosravi%2CA&author=Gafni%2CRI&author=Collins%2CMT)
Enlace
https://link.springer.com/article/10.1007/s00393-018-0510-x
Resumir
The article discusses various studies on vitamin D deficiency and its impact on health. Studies show that vitamin D deficiency is prevalent in Europe and can have negative effects on skeletal muscle, bone health, and overall metabolism. Certain medications, such as HIV-protease inhibitors and efavirenz, have been found to impair vitamin D bioactivation and lead to severe deficiencies. Glucocorticoid use has also been associated with low levels of vitamin D. The research highlights the importance of monitoring and addressing vitamin D levels, especially in at-risk populations and individuals taking medications that may interfere with vitamin D metabolism.